Pathological characteristics of domestic pigs orally infected with the virus strain causing the first reported African swine fever outbreaks in Vietnam

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DOI

https://doi.org/10.3390/pathogens12030393

Langue de publication
Anglais
Date
2023-03-01
Type
Article
Auteur(s)
  • Nguyen, Thi Thu Huyen
  • Nguyen, Van Tam
  • Le, Phuong Nam
  • Mai, Nguyen Tuan Anh
  • Dong, Van Hieu
  • Bui, Tran Anh Dao
  • Nguyen, Thi Lan
  • Ambagala, Aruna
  • Le, Van Phan
Éditeur
MDPI

Résumé

African swine fever (ASF) is currently Vietnam’s most economically significant swine disease. The first ASF outbreak in Vietnam was reported in February 2019. In this study, VNUA/HY/ASF1 strain isolated from the first ASF outbreak was used to infect 10 eight-week-old pigs orally with 103 HAD50 per animal. The pigs were observed daily for clinical signs, and whole blood samples were collected from each animal for viremia detection. Dead pigs were subjected to full post-mortem analyses. All 10 pigs displayed acute or subacute clinical signs and succumbed to the infection between 10 to 27 (19.8 ± 4.66) days post-inoculation (dpi). The onset of clinical signs started around 4–14 dpi. Viremia was observed in pigs from 6–16 dpi (11.2 ± 3.55). Enlarged, hyperemic, and hemorrhagic lymph nodes, enlarged spleen, pneumonia, and hydropericardium were observed at post-mortem examinations.

Description

This article belongs to the special issue "Emergence and Control of African Swine Fever."

Sujet

  • Santé et sécurité,
  • Sciences et technologie

Mots-clés

  • African swine fever,
  • Peste porcine africaine,
  • Virus de la peste porcine africaine,
  • African swine fever virus,
  • African and classical swine fever,
  • ASF,
  • CSF

Droits

Creative Commons Attribution 4.0 International (CC BY 4.0)

Pagination

1-12

Évalué par les pairs

Yes

Niveau de libre accès

Or

Identifiants

ISSN
2076-0817

Article

Titre de la revue
Pathogens
Volume de la revue
12
Numéro de revue
3
Numéro de l'élément
393
Date d'acceptation
2023-02-24
Date de soumission
2022-12-15

Référence(s)

Nguyen, T. T. H., Nguyen, V. T., Le, P. N., Mai, N. T. A., Dong, V. H., Bui, T. A. D., Nguyen, T. L., Ambagala, A., & Le, V. P. (2023). Pathological characteristics of domestic pigs orally infected with the virus strain causing the first reported African swine fever outbreaks in Vietnam. Pathogens, 12(3), Article 393. https://doi.org/10.3390/pathogens12030393

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Animals

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